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Cancer Risk in Children of Mothers With Epilepsy and High-Dose Folic Acid Use During Pregnancy

In this multinational population-based study of more than 3 million pregnancies, researchers identified a 2.7-fold increased risk of cancer in children of mothers with epilepsy who immediately befo

JAMA Network
2d ago
Single-Cell Transcriptomics Identifies Pathogenic T-Helper 17.1 Cells and Pro-Inflammatory Monocytes in Immune Checkpoint Inhibitor-Related Pneumonitis

In this prospective observational study, single-cell RNA and T-cell receptor sequencing was performed on bronchoalveolar lavage fluid of 11 patients with ICI-related pneumonitis and 6 demographical

Journal for ImmunoTherapy of Cancer
2d ago
Characterization of Blood-Derived Exosomal hTERT mRNA as a Biomarker for Colon Cancer and Lynch Syndrome

Human telomerase reverse transcriptase (hTERT)- mRNA was shown to be elevated in exosomes derived from the sera of a variety of hematological and solid cancer patients.

Frontiers in Oncology
2d ago
Overall Survival With Maintenance Olaparib at a 7-Year Follow-Up in Patients With Newly Diagnosed Advanced Ovarian Cancer and a BRCA Mutation: The SOLO1/GOG 3004 Trial

With an HR for OS of 0.55 (95% CI, 0.40 to 0.76) observed with maintenance olaparib (administered for ≤ 2 years in most patients) versus placebo and 67.0% of olaparib patients (v 46.5% of

Journal of Clinical Oncology
2d ago

Spotlight

Source: The ASCO Post

Medicaid expansion under the Affordable Care Act (ACA) was associated with an increase in 2-year overall survival rates among patients newly diagnosed with cancer...

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