Phenotypic Plasticity in Circulating Tumor Cells is Associated With Poor Response to Therapy in Metastatic Breast Cancer Patients

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Phenotypic Plasticity in Circulating Tumor Cells is Associated With Poor Response to Therapy in Metastatic Breast Cancer Patients

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Mar, 13, 2023

Here we present a longitudinal study using a novel microcavity array to enrich CTCs and find that a shift from epithelial CTCs to those with a mesenchymal expression pattern is associated with inferior clinical outcomes.