A Phase 1 Study of Donor Regulatory T-Cell Infusion Plus Low-Dose Interleukin-2 for Steroid-Refractory Chronic GVHD
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A Phase 1 Study of Donor Regulatory T-Cell Infusion Plus Low-Dose Interleukin-2 for Steroid-Refractory Chronic GVHD
In the present study, we combined a single infusion of Treg-enriched lymphocytes (Treg DLI) from the original stem cell donor with in vivo Treg expansion using LD IL-2 (1 × 106 IU/m2 per day for 8 weeks) in 25 adult patients with SR-cGVHD.
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