Merck and Eisai Provide Update on Phase 3 LEAP-010 Trial Evaluating Pembrolizumab Plus Lenvatinib in Patients With Certain Types of Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Merck and Eisai Provide Update on Phase 3 LEAP-010 Trial Evaluating Pembrolizumab Plus Lenvatinib in Patients With Certain Types of Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

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 According to results of  2 planned interim analyses conducted over an 11-month period, researchers have demonstrated  that pembrolizumab plus lenavatinib provides patients with a statistically significant improvement in PFS and ORR compared to pembrolizumab alone but, does not provide improvement in OS. Due to these results the study has been closed.

 

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