Wnt Inhibitors Reduce the Unfolded Protein Response and Enhance Bortezomib-Induced Cell Death in Multiple Myeloma
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Wnt Inhibitors Reduce the Unfolded Protein Response and Enhance Bortezomib-Induced Cell Death in Multiple Myeloma
Combining TNKSi and PORCi with bortezomib resulted in a potent killing of primary MM cells, demonstrating that inhibitors of Wnt signaling might be considered as therapeutic targets in future anti-myeloma combinatorial strategies.
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