Radiation Oncology

Radiation Oncology

Long-Term Outcomes With Chemoradiotherapy Before vs After Chemotherapy in Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer

Long-term results of a German phase II trial showed similar disease outcomes, chronic toxicity, and QoL with chemoradiotherapy before vs after chemotherapy... 

The ASCO Post
Impact of Chemotherapy and Radiotherapy on the Survival of Elderly Esophageal Cancer Patients Undergoing Surgery

 Researchers investigate the potential effect of CRT on the prognosis of esophageal cancer, a common and lethal carcinoma. 

BMC Gastroenterology
Results With De-escalated Radiotherapy for HPV+ve Oral Cancer

New results from a phase 3 trial (MC1275) show that DART results in robust responses and lower toxicity as compared with standard care radiotherapy. 


Long-Term Cancer Survivors Treated With Multiple Courses of Repeat Radiation Therapy

This research aims to describe patterns of care and outcome of patients treated with multiple courses of repeat radiotherapy.

Radiation Oncology
Organ Preservation Following Short-Course Radiotherapy for Rectal Cancer

Researchers evaluate the oncological outcomes in rectal cancer patients enrolled in the W&W program who received SCRT.

BJS Open
Radioresistance of Human Cancers: Clinical Implications of Genetic Expression Signatures

Scientists integrated and analyzed clinical information and mRNA-sequencing data from cancer patients that underwent radiotherapy to suggest clinical relevance of molecular characterization. 

Frontiers in Oncology
Data Shows Low-Dose CT Screening Reduces Lung Cancer Mortality

New data supports previous studies that LDCT lung cancer screening can effectively reduce the risk of patients dying of lung cancer.

Oncology Times - Latest Articles
Added Value of Preoperative Contrast-Enhanced Mammography in Staging of Malignant Breast Lesions

Researchers evaluate the added value of CEM in preoperative staging of breast cancer in a randomized study.

BMC Cancer
Evaluation of DIBH and VMAT in Hypofractionated Radiotherapy for Left-Sided Breast Cancers After Breast-Conserving Surgery

Scientists evaluated the effects of DIBH irradiation & VMAT plans under DIBH on OAR dose deposition through a comparison of dosimetric parameters of OARs...

Technology in Cancer Research & Treatment
Development of a New poly-ε-caprolactone With Low Melting Point for Creating a Thermoset Mask Used in Radiation Therapy

In radiotherapy for head and neck cancer, a patient-specific thermoplastic mask is created to improve the patient’s positional accuracy.

Scientific Reports
Additional Radiotherapy With or Without Chemotherapy Following Endoscopic Resection for Stage I Esophageal Carcinoma

Scientists retrospectively analyzed the clinical outcomes of stage I EC patients with high-risk factors who received RT at our institution after ER.


Technology in Cancer Research & Treatment
Intermittent Radiotherapy as Alternative Treatment for Recurrent High Grade Glioma

Scientists investigate through mathematical modeling an alternative, intermittent approach for radiotherapy treatment schedules for patients with recurrent high-grade glioma.

Scientific Reports
Global Processing Provides Malignancy Evidence Complementary to the Information Captured by Humans or Machines Following Detailed Mammogram Inspection

Research investigates if the gist responses and performances of radiologists in the gist experiment viewing condition are correlated with their ratings and performances in the usual presentation...

Scientific Reports
Targeting Accuracy Considerations for Simultaneous Tumor Treating Fields Antimitotic Therapy During Robotic Hypofractionated Radiation Therapy

Research explores the target accuracy of treating CNS and SBRT patients with simultaneous TTFields and radiation therapy on a robotic radiosurgery platform with skull tracking or fiducial tracking.

Technology in Cancer Research & Treatment
Using 4DCBCT Simulation and Guidance to Evaluate Inter-Fractional Tumor Variance During SABR for Lung Tumor Within the Lower Lobe

Scientists provide a method accounting for inter-fractional tumor baseline shift and amplitude variance during lung SABR treatment for NSCLC patients.

Scientific Reports
Habitat Imaging-Based 18F-FDG PET/CT Radiomics for the Preoperative Discrimination of Non-small Cell Lung Cancer and Benign Inflammatory Diseases

Scientists develop and evaluate habitat imaging-based 18F-FDG PET/CT radiomics models for discriminating NSCLC and BID, which helps medical physicists and radiologists better diagnose NSCLC...

Frontiers in Oncology
Assessment of Radiation Sensitivity of Unresectable Intrahepatic Cholangiocarcinoma in a Series of Patients Submitted to Radioembolization with Yttrium-90 Resin Microspheres

Research calculates the radiobiological α parameter in a series of patients with unresectable intrahepatic cholangiocarcinoma (ICC) submitted to SIRT with 90Y resin microspheres.

Scientific Reports
Long-Term Results of Hypofractionation With Concomitant Boost in Patients with Early Breast Cancer

Scientists report the long-term local control and survival of patients with early breast cancer who had hypofractionated whole breast irradiation with concomitant boost.

Investigation of Predictors to Achieve Acceptable Lung Dose in T-Shaped Upper and Middle Esophageal Cancer With IMRT and VMAT

Researchers investigate whether there are predictors and cutoff points that can predict the acceptable lung dose using IMRT and VMAT in radiotherapy for upper ang middle esophageal cancer.

Frontiers in Oncology
Development of a Margin Determination Framework for Tumor-Tracking Radiation Therapy With Intraoperatively Implanted Fiducial Markers

Researchers explore the feasibility of using non-ideally implanted fiducial markers (a limited number and/or far from a target) for tracking-based lung stereotactic ablative radiotherapy (SABR). 

Frontiers in Oncology
Detailed Analysis and Radiomic Prediction of First Progression Sites of First-Line Targeted Therapy for EGFR-Mutant Lung Adenocarcinoma Patients With Systemic Metastasis

Scientists analyze the first progression sites of first-line TKI treatment for EGFR-mutant lung adenocarcinoma patients with systemic metastasis...

Frontiers in Oncology
Assessment of Lymphoma and Other Hematologic Malignancies Training Needs Among Radiation Oncology Residents

Together, the ILROG and ARRO assess current RO resident HM training opportunities, comfort with HM patient care, and interest in a dedicated HM away elective.

Journal of Cancer Education
MR-Linac Radiotherapy – The Beam Angle Selection Problem

In this study, the BAO feature was explored for rectal cancer, aiming at development of beam angle class solutions to replace time-consuming individualized beam angle selection...

Frontiers in Oncology
Intrafractional Stability of MR-Guided Online Adaptive SBRT for Prostate Cancer

This study aims to analyze the dosimetric benefit of online adaptation and to evaluate its robustness over the duration of one treatment fraction.

Radiation Oncology
Radiologic Criteria of Retropharyngeal Lymph Node Metastasis in Maxillary Sinus Cancer

Scientists determine the most appropriate radiologic criteria of metastatic retropharyngeal lymph nodes (RLNs) in patients with maxillary sinus cancer (MSC). 

Radiation Oncology
Overall Survival With Stereotactic Ablative Radiotherapy for Operable Stage IA NSCLC

Researchers indicate that overall survival in patients receiving SABR for operable stage IA NSCLC was noninferior to that in a contemporary institutional cohort of patients receiving VATS L-MLND.

The ASCO Post
Putting Radiotherapy to Best Use With CAR T-Cell Therapy in Lymphoma

Researchers examined the patterns and predictors of local failure in patients with recurrent or refractory large B-cell lymphomas following CAR T-cell therapy. 

The ASCO Post
Does Adjuvant Image-Guided Intensity-Modulated Radiotherapy for Cervical Cancer Lead to Increased Rates of Late Toxicity?

Researchers found that adjuvant IG-IMRT was associated with less late grade ≥ 2 gastrointestinal toxicity vs 3D conformal radiotherapy in women with cervical cancer...

The ASCO Post
Investigate the Dosimetric and Potential Clinical Benefits Utilizing Stereotactic Body Radiation Therapy With Simultaneous Integrated Boost Technique for Locally Advanced Pancreatic Cancer

This study performs a quantitative and comprehensive dosimetric study based on the LAPC location and patient geometry to explore the feasibility and potential clinical benefits...

Frontiers in Oncology
Radiotherapy Response Assessment of Multiple Myeloma: A Dual-Energy CT Approach With Virtual Non-Calcium Images

Research explores the feasibility of DECT VNCa imaging to assess response to RT in MM.

Frontiers in Oncology
Androgen Receptor Targeted Therapy + Radiotherapy in Metastatic Castration Resistant Prostate Cancer

Scientists investigate whether radiotherapy as MDT on oligo-progressive sites in mCRPC patients during treatment with ARTT may lead to control resistant lesions, prolonging ARTT. 

Frontiers in Oncology
Assessment of Intratumor Heterogeneity in Parametric Dynamic Contrast-Enhanced MR Images: A Comparative Study of Novel and Established Methods

Researchers evaluate the performance of the spatial gradient method in DCE-MRI-derived images of Ktrans and compare the method with histogram analyses and the Haralick method.

Frontiers in Oncology
Efficacy of Whole-Ventricular Radiotherapy in Patients Undergoing Maximal Tumor Resection for Glioblastomas Involving the Ventricle

Scientists evaluated the effectiveness of WVRT in reducing intraventricular seeding in patients with GBM and identified patients who could benefit from this approach.

Frontiers in Oncology

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