Skin Cancer

Skin Cancer

Ultrasound-Mediated Microbubble Destruction Inhibits Skin Melanoma Growth by Affecting YAP1 Translation Using Ribosome Imprinting Sequencing

In this study, tumor tissue samples are collected from 64 CMM patients.

Frontiers in Oncology
Patterns in the Development of Melanoma Across Body Sites

An international research team examined patterns in the development of melanoma in patients in Australia and the United Kingdom and shed light on possible relationships by anatomical site.

Cancer Therapy Advisor
Health-Related Quality of Life With Adjuvant Pembrolizumab vs Placebo in Resected Stage III Melanoma

An analysis of this trial shows no clinically significant decline in health-related quality of life with adjuvant pembrolizumab vs placebo in resected high-risk stage III melanoma. 

The ASCO Post

Construction and Validation of a Nomogram for Patients With Skin Cancer

Study investigators use patient data collected from the surveillance, epidemiology, and end results program database to construct and validate the model for clinical prediction of skin cancer.

Long-Term Outcomes in a Multicenter, Prospective Cohort Evaluating the Prognostic 31-Gene Expression Profile for Cutaneous Melanoma

Current guidelines for postoperative management of patients with stage I-IIA cutaneous melanoma do not recommend routine cross-sectional imaging...

JCO Precision Oncology
Checkpoint Inhibitor Therapy for Skin Cancer May be Safe in Patients With Asymptomatic COVID-19

An ongoing area of uncertainty during the SARS-CoV-2 pandemic is the safety of ICI therapy for cancer, and the theoretical possibility of exacerbated irAEs secondary to COVID-19 inflammatory pathol

Annals of Oncology
Systemic Photoprotection in Skin Cancer Prevention: Knowledge Among Dermatologists

The aim of this study is to summarize the current state of knowledge of systemic photoprotection and to evaluate the knowledge and attitude of dermatologists regarding these treatments.

Muffin Technique Micrographic Surgery for Non-Melanoma Skin Cancer

This study describes the implementation and the preliminary results of MTMS in an academic dermatology center.

Frontiers in Medicine
Anti-BRAF/Anti-MEK Targeted Therapies for Metastatic Melanoma Patients During the COVID-19 Outbreak: Experience From an Italian Skin Cancer Unit

Although melanoma has been increasing at a constant rate in the past few decades, mortality has been low, and only a small percentage of patients have developed metastatic disease.

Future Oncology
Sun Exposure During Water Sports: Do Elite Athletes Adequately Protect Their Skin Against Skin Cancer?

This study examines whether elite athletes in water sports take appropriate measures to protect their skin from the sun, and whether there are differences in this respect according to...

Bioactive Compounds for Skin Health

The present study draws attention to bioactive substances, i.e., vitamins, minerals, fatty acids, polyphenols, and carotenoids, with a particular focus on their effects on the condition of the skin

Ultradeep Sequencing Differentiates Patterns of Skin Clonal Mutations Associated With Sun-Exposure Status and Skin Cancer Burden

In ultraviolet radiation–exposed skin, mutations fuel clonal cell growth.

Repurposing of Drug Candidates for Treatment of Skin Cancer

This study aims to provide an updated overview of drugs’ repurposing to treat skin cancer and discuss future perspectives.

Frontiers in Oncology
Disease Risk Scores for Skin Cancers

Study investigators trained and validated risk prediction models for the three major types of skin cancer—basal cell carcinoma, squamous cell carcinoma, and melanoma—on a cross-sectional and longit

Skin Dendritic Cells in Melanoma Are Key for Successful Checkpoint Blockade Therapy

Immunotherapy with checkpoint inhibitors has shown impressive results in patients with melanoma, but still many do not benefit from this line of treatment.

Non-Invasive Skin Sampling of Tryptophan/Kynurenine Ratio in Vitro Towards a Skin Cancer Biomarker

Non-invasive topical sampling of Trp/Kyn can therefore serve as a promising concept for skin cancer diagnostics.

Scientific Reports
Treating Melanoma in Situ During a Pandemic with Telemedicine and a Combination of Imiquimod, 5-Fluorouracil, and Tretinoin

The recent COVID-19 pandemic has created a quandary for the physician in terms of evaluating and treating cutaneous skin cancers, particularly melanomas.

Dermatologic Therapy
Metastatic Cutaneous Squamous Cell Carcinoma Involving the Parotid Gland: Experience Outside of the Sun Belt

This study characterizes a subset of patients with metastatic head and neck cutaneous squamous cell carcinoma in a tertiary North American center and describe oncologic...

Treatment of Non-melanoma Skin Cancers in the Absence of Mohs Micrographic Surgery

This study discusses the management of non-melanoma skin cancers in settings where Mohs micrographic surgery is not readily available.

Novel Sunprotection Interventions to Prevent Skin Cancer

In Denmark, 16,500 cases of melanoma and keratinocyte cancers were registered in 2015, of which 90% could have been avoided by behavioral changes.

Novel Functions of CD147 in the Mitochondria Exacerbates Melanoma Metastasis

In this study, investigators showed that CD147 was translocated from the cell membrane to the mitochondria in advanced melanoma.

Optical Technologies for the Improvement of Skin Cancer Diagnosis

This paper reviews a variety of the optical modalities that have been used in the last years in order to improve non-invasive diagnosis of skin cancer...

pH-Responsive Nanostructures Based on Surface Active Fatty Acid-Protic Ionic Liquids for Imiquimod Delivery in Skin Cancer Topical Therapy

For topical treatment of skin cancer, the design of pH-responsive nanocarriers able to selectively release the drug in the tumor acidic microenvironment represents a reliable option for targeted de

A Brief Dermatology Curriculum in Skin Cancer Detection and Prevention to Improve Medical Student Knowledge and Confidence

While the incidence of skin cancers continues to rise, there remains a disproportionate lack of introductory training on skin cancer screening and identification of modifiable...

Use of Skin Cancer Procedures, Medicare Reimbursement, and Overall Expenditures, 2012-2017

This cohort study describes recent trends in use and payment rates and in overall expenditure for skin cancer procedures in the Medicare Part B population in the United States.

Immune Checkpoint Blockade in Advanced Cutaneous Squamous Cell Carcinoma: What Do We Currently Know in 2020?

This study focused on the differences between cSCC and cutaneous melanoma and their implications on therapy, summarize the current evidence on ICB for the treatment of...

International Journal of Molecular Sciences
Immune checkpoint inhibition therapy for advanced skin cancer in patients with concomitant hematological malignancy: a retrospective multicenter DeCOG study of 84 patients

The present study analyzed the ICI treatment outcome in advanced patients with skin cancer with a concomitant hematological malignancy.

Evaluating skin cancer chemopreventive potential of water extract of Syzygium samarangense leaves through activation of the Nrf2-mediated cellular defense system

This study evaluated skin cancer chemopreventive potential of Syzygium samarangense (wax apple) leaf water extract (WAL-WE) by activating Nrf2-mediated cellular antioxidant system.

South African Journal of Botany
Interpretable deep learning systems for multi-class segmentation and classification of non-melanoma skin cancer.

This study applied for the first-time interpretable deep learning methods simultaneously to the most common skin cancers -basal cell carcinoma, squamous cell carcinoma and...

Medical Image Analysis
A robust method for skin cancer diagnosis based on interval analysis

Early diagnosis of skin cancer from dermoscopy images significantly reduces the mortality due to this cancer. However, several reasons impact system precision. One important pr......

Evidence for a non-stochastic two-field hypothesis for persistent skin cancer risk

This study proposed persistence of the overlying epithelial cancerization field in the absence of exogenous carcinogens or promoters requires a two-field composite consisting...

Scientific Reports
Numerical study of cryosurgical treatment of skin cancer

In this study, a new mathematical model describing the cryosurgical treatment of skin cancer in multilayer tissue has been developed.

International Journal of Thermal Sciences
In situ implantable three-dimensional extracellular matrix bioactive composite scaffold for postoperative skin cancer therapy

Despite drastic improvements in surgical excision techniques, tumor recurrence has remained a significant problem over the past decades.

Chemical Engineering Journal
Efficacy of biopolymeric PVA-AuNPs and PCL-Curcumin loaded electrospun nanofibers and their anticancer activity against A431 skin cancer cell line

In this study, AuNPs were phytosynthesized from M. elangi leaf extract and were characterized.

Materials today communications
The Impact of Notch Signaling for Carcinogenesis and Progression of Nonmelanoma Skin Cancer: Lessons Learned from Cancer Stem Cells, Tumor Angiogenesis, and Beyond

Since many decades, nonmelanoma skin cancer (NMSCs) is the most common malignancy worldwide.

Advances in Experimental Medicine and Biology
Reconfigurable Vivaldi THz antenna based on graphene load as hyperbolic metamaterial for skin cancer spectroscopy

Demand for an antenna with high gain and directivity for medical sensing is necessary so the Vivaldi antenna in the THz spectrum with reconfigurable characteristics is a proper solution.

Optics Communications
Injectable multi-responsive micelle/nanocomposite hybrid hydrogel for bioenzyme and photothermal augmented chemodynamic therapy of skin cancer and bacterial infection

Activatable theranostic strategy with high specificity and sensitivity for simultaneous skin cancer therapy anti-infection remains a major challenge.

Chemical Engineering Journal
FDA Updates Hydrochlorothiazide Label for Nonmelanoma Skin Cancer

HCTZ is associated with an increased risk of nonmelanoma skin cancer, and patients who take the drug should limit sun exposure and undergo regular skin cancer screening.

FDA: Small Risk of Skin Cancer With Hydrochlorothiazide Use
Cancer Therapy Advisor
DNA Alterations Can Predict Risk for Melanoma Earlier

Melanoma can be predicted long before any suspicious moles are detected thanks to the identification of DNA mutations in individual skin cells.

Oncology Learning Network
Demographics Make a Difference in Common Skin Cancers
MedPage Today

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