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PLOS ONE

PLOS ONE
Cell-Morphodynamic Phenotype Classification With Application to Cancer Metastasis Using Cell Magnetorotation and Machine-Learning

Researchers define cell morphodynamics using a dynamic histology method which is based on multiplexed Cell Magneto-Rotation and Machine Learning. 

PLOS ONE
11/17/2021
PD-L1 Expression on Circulating Tumor Cells and Platelets in Patients With Metastatic Breast Cancer

Researchers conducted a prospective preliminary study to determine the incidence of these findings in patients with metastatic breast cancer.

PLOS ONE
11/15/2021
Cost-Effectiveness Analysis of Pembrolizumab plus Chemotherapy as First-Line Therapy for Extensive-Stage Small-Cell Lung Cancer

This study aims to assess the cost-effectiveness of adding pembrolizumab to standard first-line etoposide-platinum for patients with ES-SCLC from the US payer perspective.

PLOS ONE
11/15/2021
Role of Caveolin-1 as a Biomarker for Radiation Resistance and Tumor Aggression in Lung Cancer

The molecular basis of radio-resistance in lung cancer A549 cells by knocking down caveolin-1 gene employing CRISPR-Cas9 gene editing technology was explored by researchers. 

PLOS ONE
11/11/2021
Heart Rate Variability and Psychosocial Symptoms in Adolescents and Young Adults With Cancer

A cross-sectional secondary analysis of baseline HRV and patient-centered psychosocial outcomes from a randomized trial among AYAs with cancer is presented. 

PLOS ONE
11/04/2021
Yield of Tumor Samples With a Large Guide-Sheath in Endobronchial Ultrasound Transbronchial Biopsy for Non-Small Cell Lung Cancer

Researchers investigate the utility of a large GS kit to obtain many tumor cells in patients with NSCLC.

PLOS ONE
10/29/2021
Prognostic Impact of Sarcopenia in Patients With Head and Neck Cancer Treated With Surgery or Radiation

Scientists compare the prognostic impact of sarcopenia in patients with head and neck cancer treated with surgery or radiation.

PLOS ONE
10/29/2021
Multiparametric MRI for Assessment of Early Response to Neoadjuvant Sunitinib in Renal Cell Carcinoma

This research works to detect early response to sunitinib treatment in metastatic clear cell renal cancer using multiparametric MRI.

PLOS ONE
10/26/2021
Prospective Observational Study of Nutritional/Immunologic Indices as Predictive Biomarkers for the Response to Anti-PD-1 Drugs in NSCLC

This study investigates the clinical impact of pre-treatment nutritional/immunologic indices and early post-treatment changes in the indices on treatment outcomes in advanced NSCLC. 

PLOS ONE
10/22/2021
Subcutaneous Immunoglobulin Replacement for Treatment of Humoral Immune Dysfunction in Patients With Chronic Lymphocytic Leukemia

Researchers determine the prevalence of humoral immunodeficiency in patients with CLL and serum IgG ≥ 400 mg/dL & evaluate the efficacy of SCIG...

PLOS ONE
10/15/2021
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