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Cancers

Cancers
Intersection of DNA Repair Pathways and the Immune Landscape Identifies PD-L2 as a Prognostic Marker in Epithelial Ovarian Cancer

Study investigators examine the interaction between DNA repair proteins and immune biomarkers and their association with survival in 181 cases of epithelial ovarian carcinoma. 

Cancers
04/20/2021
Non-Small-Cell Lung Cancer: New Rare Targets—New Targeted Therapies—State of The Art and Future Directions

The use of novel therapeutic drugs in lung cancer has changed the paradigm of the diagnosis and treatment of lung cancer.

Cancers
04/12/2021
The Fusion Gene Landscape in Taiwanese Patients With Non–Small-Cell Lung Cancer

Study investigators characterize the fusion gene landscape of NSCLC in a case study of Taiwanese lung cancer patients.

Cancers
03/16/2021
Treatments and Outcomes in Stage I Extranodal Marginal Zone Lymphoma in the United States

The present study assesses the SEER database aiming to examine management and survival of localized EMZL. 

Cancers
04/09/2021
Increased Pathway Complexity Is a Prognostic Biomarker in Metastatic Castration-Resistant Prostate Cancer

This study investigates whether grouping genomic alterations with other events within the same cellular pathways would offer increased precision for biomarker discovery. 

Cancers
03/30/2021
Cross-Resistance to Abiraterone and Enzalutamide in Castration Resistance Prostate Cancer Cellular Models Is Mediated by AR Transcriptional Reactivation

Study investigators demonstrate that in hormonal sensitive human prostate cancer cells the combination therapy of Abiraterone plus Enzalutamide reduced cell growth and survival. 

Cancers
03/23/2021
Immune-Checkpoint Inhibitors in Platinum-Resistant Ovarian Cancer

The aim of this review is to describe the immunobiology of ovarian cancer and likely benefit from immunotherapy, discuss clinical trial data and biomarkers that warrant further exploration...

Cancers
04/01/2021
Small Molecules in the Treatment of Squamous Cell Carcinomas: Focus on Indirubins

This review discusses the genetic landscape of squamous cell carcinoma and the related to the potential targets of indirubin-based small molecules in cancer therapy.

Cancers
04/07/2021
Cutaneous Squamous Cell Carcinoma in Patients With Hidradenitis Suppurativa

Cutaneous squamous cell carcinoma is a recognized but infrequent complication of hidradenitis suppurativa.

Cancers
03/08/2021
Cutaneous Squamous Cell Carcinoma in the Age of Immunotherapy

Expanded applications of programmed death-1 (PD-1) blockade therapies have revealed cSCC to be one of the most amenable targets.

Cancers
03/08/2021
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