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Scientific Reports

Scientific Reports
Ruxolitinib Early Administration Reduces Acute GVHD After Alternative Donor Hematopoietic Stem Cell Transplantation in Acute Leukemia

This study aims to observe the safety and clinical efficacy of early application of ruxolitinib to prevent aGVHD after alternative donor transplantation in acute leukemia.

Scientific Reports
04/19/2021
Distinct DNA Methylation Patterns Associated With Treatment Resistance in Metastatic Castration Resistant Prostate Cancer

Investigating the dynamics of the methylation changes going from the castration sensitive to the tNEPC state would provide insights into novel mechanisms of resistance. 

Scientific Reports
03/23/2021
Cell-Free DNA Concentration and Fragment Size as a Biomarker for Prostate Cancer

This study investigates whether differences in cfDNA concentration and cfDNA fragment size could improve the sensitivity for detecting more advanced and aggressive prostate cancer.

Scientific Reports
03/03/2021
Gene Expression Profile Association With Poor Prognosis in Epithelial Ovarian Cancer Patients

Study investigators perform gene expression profiling of different subtypes of ovarian cancer to evaluate its association with patient overall survival and aggressive forms of the disease.

Scientific Reports
03/08/2021
Karonudib Has Potent Anti-Tumor Effects in Preclinical Models of B-Cell Lymphoma

Study investigators test the efficacy of karonudib in vitro and in preclinical B-cell lymphoma models. 

Scientific Reports
03/18/2021
Correlation Between Family History and Characteristics of Breast Cancer

Herein, study investigators researched the link between family history and breast cancer features to elucidate the importance of family history in the diagnosis and treatment of breast cancer. 

Scientific Reports
03/18/2021
Comprehensive Analysis of Mutational and Clinicopathologic Characteristics of Poorly Differentiated Colorectal Neuroendocrine Carcinomas

This study aims to investigate clinicopathologic characteristics of colorectal NECs and elucidate genomic differences and similarities between colorectal NECs and colorectal adenocarcinomas.

Scientific Reports
03/18/2021
Suppression of Multiple Myeloma by Mitochondrial Targeting

Treatment of multiple myeloma aims at inducing cell apoptosis by surpassing the limited capacity of MM cells to cope with oxidative stress.

Scientific Reports
03/12/2021
A Highly Expressed mRNA Signature for Predicting Survival in Patients With Stage I/II Non–Small-Cell Lung Cancer After Operation

This study explores mRNA signature closely related to the prognosis of NSCLC by new algorithm of bioinformatics.

Scientific Reports
03/12/2021
Expression of Inflammatory Interleukins and Selected miRNAs in Non-Small Cell Lung Cancer

Study investigators examine the mRNA expression of interleukins IL-1β, IL-6, IL-17 and miR-9, miR-122 as potential useful biomarkers of NSCLC.

Scientific Reports
03/03/2021
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