Approaches for relapsed CLL after chemotherapy-free frontline regimens

Novel agents, including Bruton’s tyrosine kinase inhibitors have fundamentally changed the CLL treatment landscape, allowing for a chemotherapy-free paradigm for many.

Preventing and monitoring for tumor lysis syndrome and other toxicities of venetoclax during treatment of chronic lymphocytic leukemia

Recent developments in the management of CLL have moved the standard of care away from chemoimmunotherapy to targeted agents such as oral kinase inhibitors or...

Standard treatment approaches for relapsed/refractory chronic lymphocytic leukemia after frontline chemoimmunotherapy

In this article, the management of patients with relapsed/refractory CLL is discussed, with a particular emphasis on the role of PIs.

Strategies for introducing palliative care in the management of relapsed or refractory aggressive lymphomas

This article reviews benefits of primary and specialty palliative care for patients with relapsed/refractory aggressive lymphomas and barriers to such care.

Management of toxicities associated with targeted therapies for Acute Myeloid Leukemia: When to Push Through and When to Stop

The goal of this review is to help clinicians determine the risk:benefit ratio in decision making for individual patients with AML.

Does patient fitness play a role in determining first-line treatment of acute myeloid leukemia?

This study presents cases of three patients with AML with varying cytogenetic and molecular risks to demonstrate the important but changing role of patient fitness in the current...

CAR T cells for other pediatric non–B-cell hematologic malignancies

As CAR T-cell therapy has advanced in B-cell acute lymphoblastic leukemia, research is now underway to develop similar therapies for other lymphoid and myeloid malignancies for pediatric patients. 

How Do I Sequence Therapy for Follicular Lymphoma?

In the past decade, many new agents have been introduced for the management of follicular lymphoma, and therapeutic strategies have evolved over time.

Real-world analysis of treatment patterns and clinical outcomes in patients with newly diagnosed chronic lymphocytic leukemia from seven Latin American countries

The purpose of this study was to describe chronic lymphocytic leukemia treatment patterns and patient outcomes in Latin America.

Haploidentical stem cell transplantation vs matched unrelated donor transplantation in adults with hematologic malignancies: a systematic review and meta-analysis.

Haploidentical hematopoietic stem cell transplantation and matched unrelated donor transplantation are two important options when a matched sibling donor is unavailable.

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