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Phytomedicine

Phytomedicine
Effect of pristimerin on apoptosis through activation of ROS/ endoplasmic reticulum (ER) stress-mediated noxa in colorectal cancer.

This study aimed to investigate the mechanisms of pristimerin-induced apoptosis against CRC in vitro and in vivo.

Phytomedicine
01/01/2021
Functional proteomic analysis reveals that fungal immunomodulatory protein reduced expressions of heat shock proteins correlates to apoptosis in lung cancer cells.

This study determines the changes in the proteomic profile for tumor lesions of LLC1 cell-bearing mouse received with LZ-8 and the potential mechanism for FIPs in anti-lung cancer cells.

Phytomedicine
01/01/2021
Licochalcone A inhibits interferon-gamma-induced programmed death-ligand 1 in lung cancer cells.

The aim of this study is to further clarify the effect and the mechanism of LCA on inhibiting IFN-γ-induced PD-L1 in lung cancer cells.

Phytomedicine
01/01/2021
Effect of the isoflavone corylin from cullen corylifolium on colorectal cancer growth, by targeting the STAT3 signaling pathway.

The purpose of this study was to analyze the antitumor activity of corylin in CRC and to elucidate its molecular mechanisms of action.

Phytomedicine
01/01/2021
Ginkgetin derived from Ginkgo biloba leaves enhances the therapeutic effect of cisplatin via ferroptosis-mediated disruption of the Nrf2/HO-1 axis in EGFR wild-type non-small-cell lung cancer

Cisplatin is the first-in-class drug for advanced and non-targetable NSCLC.

Phytomedicine
01/01/2021
Targeted inhibition of c-MET by podophyllotoxin promotes caspase-dependent apoptosis and suppresses cell growth in gefitinib-resistant non-small cell lung cancer cells.

In the present study, the authors investigated the underlying mechanisms of PPT-induced apoptosis in NSCLC cells and found that the inhibition of c-MET kinase activity...

Phytomedicine
01/01/2021
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