Cancer Management and Research

Cancer Management and Research
Real-World, Single-Center Data for Lenalidomide Plus Rituximab in Relapsed or Refractory Diffuse Large B-Cell Lymphoma and Transformed Follicular Lymphoma

This study explores the efficacy of lenalidomide plus rituximab for patients with R/R DLBCL including cases of secondary CNS involvement and transformed FL in real-world context because...

Cancer Management and Research
Further Understanding of the Immune Microenvironment in Head and Neck Squamous Cell Carcinoma: Implications for Prognosis

Investigators review the literature on the tumor microenvironment as a key player in tumor growth and anti-cancer treatment responses in head and neck cancer.

Cancer Management and Research
Chemotherapy-Free Management of Follicular and Marginal Zone Lymphoma

Emerging data with novel forms of immunotherapy suggest that immune-directed approaches can produce very high and potentially durable responses in FL/MZL with limited toxicities, further...

Cancer Management and Research
Normal Basal Epithelial Cells Stimulate the Migration and Invasion of Prostate Cancer Cell RM-1 by TGF-β1/STAT3 Axis in vitro

This study aims to investigate whether basal epithelial cells could suppress migration and invasion of prostate cancer cells to become a new treatment strategy for prostate cancer.

Cancer Management and Research
Clinical Significance of miR-183-3p and miR-182-5p in NSCLC and Their Correlation

This study evaluates the clinicopathologic significance of miR-183-3p and miR-182-5p, and the role of miR-183-3p in NSCLC progression.

Cancer Management and Research
IL-37 Was Involved in Progress of Acute Myeloid Leukemia Through Regulating IL-6 Expression

The aim of this study is to evaluate IL-37 as a prognostic factor and its possible mechanism of action.

Cancer Management and Research
Cellular Mechanism of Gene Mutations and Potential Therapeutic Targets in Ovarian Cancer

This review illustrates recent advances in identifying ovarian cancer gene mutations, including those of TP53, BRCA1/2, PIK3CA, and KRAS genes.

Cancer Management and Research
WNT5a in Colorectal Cancer: Research Progress and Challenges

In patients with colorectal cancer, WNT5a triggers a variety of downstream signaling pathways, which mainly affect the migration and invasion of tumor cells.

Cancer Management and Research
Rechallenge With Multi-Targeted Tyrosine Kinase Inhibitors in Patients With Advanced Soft Tissue Sarcoma

This retrospective study investigates the efficacy and safety of multi-targeted TKI rechallenge in patients with advanced soft tissue sarcoma after the failure of previous TKI treatment.

Cancer Management and Research
Improving Social Support to Increase QoL in Lung Cancer Patients

The purpose of this study is to analyze original papers in order to determine whether an increase in social support is important in improving QoL for lung cancer patients. 

Cancer Management and Research
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