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OncoTargets and Therapy

OncoTargets and Therapy
Treatment Strategies for Metastatic Castration-Sensitive Prostate Cancer: From “All-Comers” to “Personalized” Approach

A remarkable evolution in the treatment of mCSPC has been noted in the previous several years.

OncoTargets and Therapy
05/05/2021
Targeted Therapy For RET-Rearranged Non-Small Cell Lung Cancer: Clinical Development And Future Directions

Novel selective RET inhibitors like BLU-667, LOXO-292 and RXDX-105 have been recently investigated in early phase clinical trials showing promising efficacy with a manageable toxicity profile.

OncoTargets and Therapy
Current and Emerging Therapeutic Options for Hairy Cell Leukemia Variant

This review examines the diagnostic criteria and clinical characteristics of HCL-v and presents a comprehensive overview of current therapeutic options in HCL-v.

OncoTargets and Therapy
03/09/2021
Single-Cell Sequencing, an Advanced Technology in Lung Cancer Research

This review summarizes lung cancer research using SCS and their research achievements.

OncoTargets and Therapy
03/16/2021
Estimating Survival in Patients with Non-Small-Cell Lung Cancer and Brain Metastases: A Verification of the Graded Prognostic Assessment for Lung Cancer Using Molecular Markers

This study aims to validate the feasibility of the Lung-molGPA in NSCLC.

OncoTargets and Therapy
03/02/2021
Immune Regulation of the cGAS-STING Signaling Pathway in the Tumor Microenvironment and Its Clinical Application

STING agonists, as novel agonists, are used in preclinical research and in the treatment of various tumors via clinical trials and have displayed attractive application prospects.

OncoTargets and Therapy
03/01/2021
Increased HSF1 Promotes Infiltration and Metastasis in Cervical Cancer via Enhancing MTDH-VEGF-C Expression

The purpose of this study is to explore the molecular mechanism of promoting cervical cancer by HSF1 in vivo and in vitro.

OncoTargets and Therapy
02/26/2021
Promising Molecular Targets for the Targeted Therapy of Biliary Tract Cancers

In this article, a comprehensive review is conducted to examine potential molecular targets for BTC targeted therapy and their mechanisms.

OncoTargets and Therapy
02/25/2021
Hypofractionated Low-Dose Radiotherapy Combined with Immune Checkpoint Inhibition in Metastatic Solid Tumors

This retrospective cohort study includes 32 patients with metastatic solid tumors treated with hypofractionated radiotherapy combined with an immune checkpoint inhibitor.

OncoTargets and Therapy
02/04/2021
Successful Use of Nivolumab in a Patient with Head and Neck Cancer After Allogeneic Bone Marrow Transplantation

Recently, programmed cell death 1(PD-1) inhibitors have shown a significant curative effect in the treatment of most solid cancers and some hematological malignancies.

OncoTargets and Therapy
02/10/2021
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