OncoTargets and Therapy

OncoTargets and Therapy
A Immune-Related Signature Associated with TME Can Serve as a Potential Biomarker for Survival and Sorafenib Resistance in Liver Cancer

This research team worked to develop a robust TME-related prognostic signature that could independently predict both RFS and OS of LIHC. 

OncoTargets and Therapy
Nanoparticle T cell Engagers for the Treatment of Acute Myeloid Leukemia

Study investigator findings suggest that nanoTCE technology is a novel and promising immuno-therapy for the treatment of AML.

OncoTargets and Therapy
Identification and Experimental Validation of Immune-Associate lncRNAs for Predicting Prognosis in Cervical Cancer

This study aimed to identify an immune-related lncRNA signature for the prospective assessment of prognosis in CC patients.

OncoTargets and Therapy
Treatment Strategies for Metastatic Castration-Sensitive Prostate Cancer: From “All-Comers” to “Personalized” Approach

A remarkable evolution in the treatment of mCSPC has been noted in the previous several years.

OncoTargets and Therapy
Targeted Therapy For RET-Rearranged Non-Small Cell Lung Cancer: Clinical Development And Future Directions

Novel selective RET inhibitors like BLU-667, LOXO-292 and RXDX-105 have been recently investigated in early phase clinical trials showing promising efficacy with a manageable toxicity profile.

OncoTargets and Therapy
Current and Emerging Therapeutic Options for Hairy Cell Leukemia Variant

This review examines the diagnostic criteria and clinical characteristics of HCL-v and presents a comprehensive overview of current therapeutic options in HCL-v.

OncoTargets and Therapy
Single-Cell Sequencing, an Advanced Technology in Lung Cancer Research

This review summarizes lung cancer research using SCS and their research achievements.

OncoTargets and Therapy
Estimating Survival in Patients with Non-Small-Cell Lung Cancer and Brain Metastases: A Verification of the Graded Prognostic Assessment for Lung Cancer Using Molecular Markers

This study aims to validate the feasibility of the Lung-molGPA in NSCLC.

OncoTargets and Therapy
Immune Regulation of the cGAS-STING Signaling Pathway in the Tumor Microenvironment and Its Clinical Application

STING agonists, as novel agonists, are used in preclinical research and in the treatment of various tumors via clinical trials and have displayed attractive application prospects.

OncoTargets and Therapy
Increased HSF1 Promotes Infiltration and Metastasis in Cervical Cancer via Enhancing MTDH-VEGF-C Expression

The purpose of this study is to explore the molecular mechanism of promoting cervical cancer by HSF1 in vivo and in vitro.

OncoTargets and Therapy
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