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Nature Communications

Nature Communications
PAX8 and MECOM Are Interaction Partners Driving Ovarian Cancer

Comprehensive genomic screens furthermore indicate an additional oncogenic role for PAX8 in renal and ovarian cancers.

Nature Communications
04/26/2021
A Clinical Transcriptome Approach to Patient Stratification and Therapy Selection in Acute Myeloid Leukemia

Study investigators develop and validate a clinical transcriptome-based assay for stratification of acute myeloid leukemia.

Nature Communications
04/30/2021
Targeting NSD2-Mediated SRC-3 Liquid–Liquid Phase Separation Sensitizes Bortezomib Treatment in Multiple Myeloma

This study finds that high steroid receptor coactivator-3 expression is correlated with relapse/refractory and poor outcomes in MM patients treated with bortezomib-based regimens.

Nature Communications
02/15/2021
A Pediatric Brain Tumor Atlas of Genes Deregulated by Somatic Genomic Rearrangement

The global impact of somatic structural variants on gene expression in pediatric brain tumors has not been thoroughly characterised.

Nature Communications
02/10/2021
Integrative Molecular Characterization of Sarcomatoid and Rhabdoid Renal Cell Carcinoma

Study investigators evaluate multiple clinical trial and real-world cohorts of S/R RCC to characterize their molecular features, clinical outcomes, and immunologic characteristics.

Nature Communications
02/05/2021
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