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Prognostic Value of Baseline and Interim Positron Emission Tomography Markers in Diffuse Large B-cell Lymphoma Patients

Optimal PET parameters and imaging time points to prognosticate PFS as well as OS of patients with DLBCL have not been established.

Hemasphere
07/13/2021
Induced Pluripotent Stem Cells Enable Disease Modeling and Drug Screening in Calreticulin del52 and ins5 Myeloproliferative Neoplasms

Mutations in the calreticulin gene are seen in about 30% of essential thrombocythemia and primary myelofibrosis patients.

Hemasphere
06/12/2021
Functional Consequences of Mutations in Myeloproliferative Neoplasms

The most prevalent mutation, JAK2 V617F, is associated with the 3 entities polycythemia vera, essential thrombocythemia, and myelofibrosis, while CALR and MPL mutations are associated only with ET

Hemasphere
06/01/2021
Allogeneic Stem Cell Transplantation Platforms With Ex Vivo and In Vivo Immune Manipulations: Count and Adjust

This review focuses on the impact of in vivo and ex vivo graft manipulation on immune reconstitution and clinical outcome.

Hemasphere
06/01/2021
Immunomodulatory Therapies for the Treatment of Graft-versus-host Disease

The transfer of immunomodulatory and immunosuppressive cell populations, including mesenchymal stromal cells and regulatory T-cells, show promising results in GvHD treatment.

Hemasphere
06/01/2021
EHA Endorsement of ESMO Clinical Practice Guidelines for Newly Diagnosed and Relapsed Follicular Lymphoma

The ESMO Clinical Practice Guidelines for diagnosis, treatment, and follow-up for Follicular Lymphoma released in the late 2020 in accordance with the ESMO standard operating procedures for...

Hemasphere
04/21/2021
SARS-CoV-2 Vaccines in Patients With Multiple Myeloma

In both a pooled analysis of 23 studies with data from 412 patients with MM and a retrospective study including 650 patients with MM and COVID-19, the estimated risk of death due to COVID-19 was 33

Hemasphere
02/17/2021
Precision Medicine in Hematology 2021: Definitions, Tools, Perspectives, and Open Questions

Although the emerging roles of precision medicine and personalized medicine in hematology and oncology are clearly visible, several questions remain.

Hemasphere
02/17/2021
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