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Journal of Translational Medicine

Journal of Translational Medicine
Inhibition of EZH2 by Chidamide Exerts Antileukemia Activity and Increases Chemosensitivity Through Smo/Gli-1 Pathway in Acute Myeloid Leukemia

Aberrant activation of HDACs results in uncontrolled proliferation and blockade of differentiation, and HDAC inhibition has been investigated as epigenetic therapeutic strategy against AML.

Journal of Translational Medicine
03/21/2021
High Lymphocyte Population-Related Predictive Factors for a Long-Term Response in Non-Small Cell Lung Cancer Patients Treated With Pemetrexed

This study investigates the clinical characteristics and predictive factors in patients with advanced NSq-NSCLC who underwent long-term PEM maintenance therapy.

Journal of Translational Medicine
02/28/2021
Genome-Wide Analysis Identifies Critical DNA Methylations Within NTRKs Genes in Colorectal Cancer

The following study investigates the methylation and expression profiles and prognostic value of NTRKs gene in colorectal cancer.

Journal of Translational Medicine
02/16/2021
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