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BMC Medicine

BMC Medicine
Polygenic Risk Score Across Distinct Colorectal Cancer Screening Outcomes

Researchers elucidate the utility of the PRS as a second test after a FIT positive result to indicate or prioritize a colonoscopy.

BMC Medicine
11/08/2021
Comparison of Submucosal and Subserosal Approaches Toward Optimized Indocyanine Green Tracer-Guided Laparoscopic Lymphadenectomy for Patients With Gastric Cancer (FUGES-019): A Randomized Controlled Trial

Researchers compare the efficacy and ICG injection between the preoperative submucosal and intraoperative subserosal approaches for LN tracing during laparoscopic gastrectomy.

BMC Medicine
10/27/2021
Clinical and Molecular Feature-Based Nomogram Model for Predicting Benefit From Bevacizumab Combined with First-Generation EGFR-TKI in EGFR-Mutant Advanced NSCLC

Scientists investigate factors affecting the efficacy of first-gen EGFR-TKI with or without bevacizumab and identify the subset of patients who can benefit from combination therapy.

BMC Medicine
10/19/2021
Identification and Validation of Tissue or ctDNA PTPRD Phosphatase Domain Deleterious Mutations as Prognostic and Predictive Biomarkers for Immune Checkpoint Inhibitors in Non-Squamous NSCLC

Scientists report that the tissue and ctDNA PTPRD phosphatase domain mutations functioned as a prognostic biomarker predicting higher ORR and favorable PFS of ICIs.

BMC Medicine
10/08/2021
Utility of Comprehensive Genomic Profiling in Directing Treatment and Improving Patient Outcomes in Advanced Non-Small Cell Lung Cancer

Researchers provide a re-evaluation on the clinical implications of comprehensive genomic profiling in the current treatment landscape of advanced NSCLC.

BMC Medicine
10/01/2021
Vegetable Intake and the Risk of Bladder Cancer in the BLadder Cancer Epidemiology and Nutritional Determinants (BLEND) International Study

This research aims to elucidate the association between vegetable intake and bladder cancer risk by conducting a pooled analysis of data from prospective cohort studies.

BMC Medicine
03/09/2021
Automated Detection of Lung Nodules and Coronary Artery Calcium Using Artificial Intelligence on Low-Dose CT Scans for Lung Cancer Screening

This study presents findings on the performance of an AI convolutional neural network prototype that automatically detects pulmonary nodules and quantifies coronary artery calcium volume...

BMC Medicine
03/04/2021
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