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Epigenomic Reprogramming toward Mesenchymal-Epithelial Transition in Ovarian-Cancer-Associated Mesenchymal Stem Cells Drives Metastasis

This study shows that in addition to cancer cell EMT, ovarian cancer cell metastasis relies on an epigenomic mesenchymal-to-epithelial transition in host mesenchymal stem cells.

12/18/2020
Ovarian Cancer Cells Cooperate to Metastasize

The team isolated subpopulations of cells from human ovarian tumors and found that none had the ability to form metastatic tumors on its own. 

Oncology Times - Latest Articles
12/20/2020

Ixazomib and Daratumumab Demonstrate Tolerable Safety for Elderly Patients with Relapsed/Refractory MM

According to new data, combination ixazomib and daratumumab, without dexamethasone, was tolerable in elderly and frail patients with R/R MM.

Oncology Learning Network
12/01/2021
Safety and Tolerability Analysis of Melflufen plus Dexamethasone in Patients with Relapsed/Refractory MM

Safety and tolerability data from the OP-103 study found that melflufen plus dexamethasone remained consistent with prior reports; these data were presented at the 63rd ASH Annual Meeting.

Oncology Learning Network
12/01/2021
Ixazomib plus Pomalidomide and Dexamethasone Shows Promise in R/R MM

Results of a phase 1/2 multicenter trial showed that twice-weekly ixazomib added to pomalidomide and dexamethasone treatment was a well-tolerated and promising treatment option...

Oncology Learning Network
11/23/2021

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